Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | GLS | O94925 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787727 | 0.87 | AHR (0.52) | AHRGLSSLC6A4HTR1ADAO | |
| SCHEMBL5616200 | 0.83 | SLC6A4 (0.43) | AHRGLSSLC6A4HTR1ADAO | |
| SCHEMBL8655960 | 0.83 | MPO (0.46) | AHRGLSSLC6A4HTR1ADAO | |
| SCHEMBL11032690 | 0.83 | GLS (0.45) | AHRGLSSLC6A4HTR1ADAO | |
| SCHEMBL8655958 | 0.83 | HTR1A (0.43) | AHRGLSSLC6A4HTR1ADAO | |
| SCHEMBL14893124 | 0.81 | BID (0.45) | AHRGLSSLC6A4HTR1AGPR84 | |
| SCHEMBL9225111 | 0.81 | BID (0.45) | AHRGLSSLC6A4HTR1AGPR84 | |
| SCHEMBL3792774 | 0.81 | AHR (0.44) | AHRGLSSLC6A4HTR1ADAO | |
| SCHEMBL1962511 | 0.81 | AHR (0.44) | AHRGLSSLC6A4HTR1ADAO | |
| SCHEMBL1880679 | 0.81 | AHR (0.44) | AHRGLSSLC6A4HTR1ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164633-A2 | Indole derivatives | MERCK PATENT GmbH (DE) | 1985-12-18 | — | — | EP | disclosed |