Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116038 | 0.85 | TSHR (0.43) | HSPB1ALDH1A1TP53EPAS1TDP1 | |
| SCHEMBL10970098 | 0.82 | HPGD (0.52) | MAPTSMN1; SMN2HSPB1ALDH1A1PIN1 | |
| SCHEMBL10519544 | 0.78 | MAPT (0.41) | MAPTALDH1A1KDM4ECRHBPCRHR2 | |
| SCHEMBL11401947 | 0.77 | KDM4E (0.48) | MAPTALDH1A1L3MBTL1KDM4ECRHBP | |
| SCHEMBL19189611 | 0.74 | L3MBTL1 (0.45) | MAPTSMN1; SMN2HSPB1ALDH1A1PIN1 | |
| SCHEMBL11411623 | 0.73 | MEN1 (0.38) | MAPTSMN1; SMN2HSPB1ALDH1A1NPSR1 | |
| SCHEMBL6117 | 0.72 | TDP1 (0.53) | MAPTSMN1; SMN2HSPB1ALDH1A1L3MBTL1 | |
| SCHEMBL30297160 | 0.72 | TDP1 (0.53) | MAPTSMN1; SMN2HSPB1ALDH1A1L3MBTL1 | |
| SCHEMBL10766268 | 0.72 | TDP1 (0.42) | MAPTSMN1; SMN2HSPB1ALDH1A1NPSR1 | |
| SCHEMBL1341322 | 0.71 | L3MBTL1 (0.46) | MAPTSMN1; SMN2HSPB1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |