Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPD | P32754 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972478 | 0.85 | MAPT (0.41) | TSHRCDK2ALDH1A1TP53HPGD | |
| SCHEMBL10970098 | 0.78 | HPGD (0.52) | ALDH1A1KMT2AHPGDHSPB1MEN1 | |
| SCHEMBL10337477 | 0.76 | ALDH1A1 (0.33) | CDK2ALDH1A1TP53HPDKMT2A | |
| SCHEMBL9120594 | 0.76 | MEN1 (0.52) | TSHRALDH1A1KMT2AMAPK1HPGD | |
| SCHEMBL11401947 | 0.73 | KDM4E (0.48) | ALDH1A1KMT2AMAPK1HPGD | |
| SCHEMBL11092742 | 0.73 | HPGD (0.56) | TSHRCDK2ALDH1A1TP53KMT2A | |
| SCHEMBL11168463 | 0.73 | TDP1 (0.51) | CDK2KMT2AEPAS1CCR2MEN1 | |
| SCHEMBL28075340 | 0.72 | EPAS1 (0.51) | TSHRCDK2KMT2AEPAS1CCR2 | |
| SCHEMBL29740471 | 0.72 | PKM (0.59) | TSHRCDK2PKMALDH1A1KMT2A | |
| SCHEMBL104452 | 0.72 | PKM (0.59) | TSHRCDK2PKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435588-A | 2'-CHLORO-4'-TRIFLUOROMETHYL-PHENOXY-3-BENZOATE DERIVATIVES | GAF CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |