Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411623 | 0.83 | MEN1 (0.38) | HPGDL3MBTL1ALDH1A1TDP1HSPB1 | |
| SCHEMBL11401947 | 0.82 | KDM4E (0.48) | HPGDL3MBTL1ALDH1A1HTTATM | |
| SCHEMBL10972478 | 0.82 | MAPT (0.41) | HPGDL3MBTL1ALDH1A1TDP1HSPB1 | |
| SCHEMBL11116038 | 0.78 | TSHR (0.43) | HPGDALDH1A1TDP1HSPB1MEN1 | |
| SCHEMBL11287905 | 0.77 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1TDP1HSPB1HTT | |
| SCHEMBL10766268 | 0.76 | TDP1 (0.42) | L3MBTL1ALDH1A1TDP1HSPB1HTT | |
| SCHEMBL10947425 | 0.74 | GPR35 (0.39) | ALDH1A1TDP1HTTLMNASMN1; SMN2 | |
| SCHEMBL1338743 | 0.73 | HSPB1 (0.60) | HPGDL3MBTL1ALDH1A1TDP1HSPB1 | |
| SCHEMBL10890833 | 0.73 | MAPT (0.37) | HPGDL3MBTL1ALDH1A1TDP1HTT | |
| SCHEMBL9120594 | 0.72 | MEN1 (0.52) | HPGDALDH1A1TDP1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |