Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CHAT | P28329 | 1/20 | 0.63 |
| ▸ | KDM4A | O75164 | 1/20 | 0.55 |
| ▸ | KDM4B | O94953 | 1/20 | 0.55 |
| ▸ | PYGL | P06737 | 8/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973260 | 1.00 | ALDH1A1 (0.64) | ALDH1A1CHATKDM4AKDM4BPYGL | |
| SCHEMBL9720849 | 0.97 | CHAT (0.67) | ALDH1A1CHATKDM4AKDM4BPYGL | |
| SCHEMBL9720852 | 0.97 | CHAT (0.67) | ALDH1A1CHATKDM4AKDM4BPYGL | |
| SCHEMBL11464283 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CHATKDM4AKDM4BPYGL | |
| SCHEMBL10712182 | 0.88 | CHAT (0.58) | ALDH1A1CHATKDM4AKDM4BPYGL | |
| SCHEMBL19036493 | 0.88 | CHAT (0.58) | ALDH1A1CHATKDM4AKDM4BPYGL | |
| SCHEMBL10712185 | 0.88 | CHAT (0.58) | ALDH1A1CHATKDM4AKDM4BPYGL | |
| SCHEMBL19036498 | 0.86 | CHAT (0.61) | ALDH1A1CHATKDM4AKDM4BPYGL | |
| SCHEMBL30749650 | 0.86 | NQO2 (0.57) | ALDH1A1CHATTP53KMT2AGUSB | |
| SCHEMBL265106 | 0.85 | CHAT (0.55) | ALDH1A1CHATKDM4AKDM4BPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533505-A | REACTION OF ETHYLENE IWITH ACID HALIDES IN THE PRESENCE OF A BASE AND A PALLADIUM CATALYST | CIBA-GEIGY CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0062005-B1 | PROCESS FOR THE MANUFACTURE OF STYRENE AND/OR STILBENE DERIVATIVES | CIBA-GEIGY AG (CH) | 1985-06-26 | — | — | EP | disclosed |
| EP-0062005-A1 | Process for the manufacture of styrene and/or stilbene derivatives | CIBA-GEIGY AG (CH) | 1982-10-06 | — | — | EP | disclosed |