Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | KDM4B | O94953 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 7/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720852 | 1.00 | CHAT (0.67) | CHATALDH1A1KDM4AKDM4BPYGL | |
| SCHEMBL10973255 | 0.97 | ALDH1A1 (0.64) | CHATALDH1A1KDM4AKDM4BPYGL | |
| SCHEMBL10973260 | 0.97 | ALDH1A1 (0.64) | CHATALDH1A1KDM4AKDM4BPYGL | |
| SCHEMBL10712182 | 0.91 | CHAT (0.58) | CHATALDH1A1KDM4AKDM4BPYGL | |
| SCHEMBL19036493 | 0.91 | CHAT (0.58) | CHATALDH1A1KDM4AKDM4BPYGL | |
| SCHEMBL10712185 | 0.91 | CHAT (0.58) | CHATALDH1A1KDM4AKDM4BPYGL | |
| SCHEMBL30749650 | 0.89 | NQO2 (0.57) | CHATALDH1A1TP53KMT2AGUSB | |
| SCHEMBL19036498 | 0.89 | CHAT (0.61) | CHATALDH1A1KDM4AKDM4BPYGL | |
| SCHEMBL11464283 | 0.86 | ALDH1A1 (0.58) | CHATALDH1A1KDM4AKDM4BPYGL | |
| SCHEMBL8983454 | 0.83 | CHAT (0.51) | CHATALDH1A1KDM4AKDM4BPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0252009-B1 | 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | disclosed |
| EP-0252009-A1 | 1,4-Distyryl benzene compounds and their mixtures with other 1,4-distyryl benzene compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |