SCHEMBL30749650

SCHEMBL30749650

Oc1ccc(C=Cc2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 2/20 0.57
LCK P06239 1/20 0.57
CHAT P28329 1/20 0.56
HSD17B10 Q99714 3/20 0.56
APP P05067 5/20 0.56
ALDH1A1 P00352 3/20 0.56
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA3 P07451 2/20 0.56
CA4 P22748 2/20 0.56
CA6 P23280 2/20 0.56
CA5A P35218 2/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
CA13 Q8N1Q1 2/20 0.56
CA14 Q9ULX7 2/20 0.56
CA5B Q9Y2D0 2/20 0.56
KDM4E B2RXH2 2/20 0.56
MEN1 O00255 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720849 0.89 CHAT (0.67) CHATALDH1A1TP53MAOBKMT2A
SCHEMBL9720852 0.89 CHAT (0.67) CHATALDH1A1TP53MAOBKMT2A
SCHEMBL10973255 0.86 ALDH1A1 (0.64) CHATALDH1A1TP53MAOBKMT2A
SCHEMBL10973260 0.86 ALDH1A1 (0.64) CHATALDH1A1TP53MAOBKMT2A
SCHEMBL3197944 0.82 BACE1 (0.80) MAOBABCB1AKR1B1MAOAPTGS2
SCHEMBL3197932 0.82 BACE1 (0.80) MAOBABCB1AKR1B1MAOAPTGS2
SCHEMBL8967738 0.82 LCK (0.62) LCKCHATHSD17B10APPPTGS1
SCHEMBL8967731 0.82 LCK (0.62) LCKCHATHSD17B10APPPTGS1
SCHEMBL10712185 0.80 CHAT (0.58) CHATALDH1A1CYP1A2MAOBCYP1A1
SCHEMBL10712182 0.80 CHAT (0.58) CHATALDH1A1CYP1A2MAOBCYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510350-A Stilbene And-1 protein degradation agent, preparation method And application thereof 中国医学科学院放射医学研究所 2024-02-06 CN disclosed