Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976251 | 0.89 | MAPT (0.61) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL10973795 | 0.87 | MAPT (0.45) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL8508358 | 0.86 | ALDH1A1 (0.51) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL733453 | 0.86 | MAPT (0.53) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL10838995 | 0.85 | MAPT (0.45) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL11299600 | 0.83 | ALDH1A1 (0.52) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL10969382 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL29393267 | 0.82 | MAPT (0.58) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL10840202 | 0.82 | MAPT (0.44) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL9420221 | 0.82 | ALDH1A1 (0.54) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082699-B1 | HERBICIDAL QUINOXALINYL ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-13 | — | — | EP | claimed |
| EP-0082699-A1 | Herbicidal quinoxalinyl ethers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-29 | — | — | EP | claimed |
| EP-0082699-B1 | HERBICIDAL QUINOXALINYL ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-13 | — | — | EP | disclosed |
| EP-0082699-A1 | Herbicidal quinoxalinyl ethers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |