Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.74 |
| ▸ | PIM1 | P11309 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ELANE | P08246 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | FGB | P02675 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417492 | 0.94 | EGFR (0.76) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL8947495 | 0.92 | EGFR (0.73) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL7792566 | 0.90 | EGFR (0.71) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL28115502 | 0.90 | EGFR (0.62) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL498666 | 0.90 | MEN1 (0.79) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL612831 | 0.88 | MAPT (0.74) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL5816933 | 0.88 | EGFR (0.64) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL11526060 | 0.87 | EGFR (0.63) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL11528272 | 0.85 | EGFR (1.00) | EGFRPIM1MAPTMEN1KMT2A | |
| SCHEMBL28575370 | 0.85 | MEN1 (0.72) | EGFRPIM1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60190732-A | — | — | None | — | — | JP | disclosed |
| JP-S60190732-A | 8-ALLYL-6,8,11-TRIHYDROXY-7,8,9,10-TETRAHYDRO-5,12- NAPHTHACENEDIONE DERIVATIVE | SAGAMI CHEM RES CENTER | 1985-09-28 | — | — | JP | disclosed |
| US-4147706-A | Intermediates for polycyclic quinonoid antibiotics | RESEARCH CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4070382-A | DAUNOMYCINS, ANTITUMOR AGENTS | RESEARCH CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |