SCHEMBL28115502

SCHEMBL28115502

COc1cccc2c1C(=O)c1c(Cl)ccc(OC)c1C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.62
PIM1 P11309 1/20 0.62
MAPT P10636 6/20 0.61
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
ALDH1A1 P00352 4/20 0.61
KDM4E B2RXH2 2/20 0.61
USP2 O75604 1/20 0.61
DUSP3 P51452 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
RAB9A P51151 5/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
MAPK1 P28482 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
HTT P42858 2/20 0.53
S1PR4 O95977 1/20 0.53
HSP90AA1 P07900 1/20 0.53
G6PD P11413 1/20 0.53
S1PR1 P21453 1/20 0.53
OPRK1 P41145 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10974170 0.90 EGFR (0.74) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL9846469 0.88 MAPT (0.79) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL11873601 0.88 MAPT (0.61) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL3417492 0.84 EGFR (0.76) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL8947495 0.82 EGFR (0.73) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL7792566 0.81 EGFR (0.71) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL498666 0.81 MEN1 (0.79) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL23271812 0.80 MAPT (0.66) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL30003259 0.80 MAPT (0.66) EGFRPIM1MAPTMEN1KMT2A
SCHEMBL5816933 0.79 EGFR (0.64) EGFRPIM1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106349294-A Aniline anthraquinone late transition metal compound and preparation method and application thereof 东华大学 2017-01-25 CN claimed