Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 9/20 | 0.51 |
| ▸ | AKR1A1 | P14550 | 6/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672018 | 0.82 | AKR1B1 (0.69) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL10930198 | 0.78 | AKR1B1 (0.55) | AKR1B1AKR1A1AKR1B10 | |
| SCHEMBL9671705 | 0.76 | AKR1B1 (0.61) | AKR1B1AKR1A1AKR1B10 | |
| SCHEMBL10929003 | 0.75 | AKR1B1 (0.60) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL9672965 | 0.72 | AKR1B1 (0.56) | AKR1B1AKR1A1AKR1B10MAPT | |
| SCHEMBL21844215 | 0.72 | AKR1B1 (0.62) | AKR1B1AKR1A1AKR1B10 | |
| SCHEMBL10345515 | 0.71 | AKR1B1 (0.55) | AKR1B1AKR1A1AKR1B10 | |
| SCHEMBL9673456 | 0.70 | AKR1B1 (0.57) | AKR1B1AKR1A1AKR1B10MAPTKMT2A | |
| SCHEMBL10929989 | 0.69 | AKR1B1 (0.56) | AKR1B1AKR1A1AKR1B10MAPTKMT2A | |
| SCHEMBL11832119 | 0.67 | MAOA (0.61) | ADRA2AADRA2BADRA2CMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537892-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1985-08-27 | — | — | US | claimed |