Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969078 | 0.94 | HTR1A (0.60) | PARP1HTR1AMAPTDRD2DRD4 | |
| SCHEMBL10972023 | 0.87 | DRD2 (0.54) | PARP1HTR1AMAPTDRD2DRD4 | |
| SCHEMBL10967600 | 0.82 | TDP1 (0.64) | PARP1HTR1AMAPTDRD2DRD4 | |
| SCHEMBL10968442 | 0.81 | DRD2 (0.55) | HTR1AMAPTDRD2DRD4DRD3 | |
| SCHEMBL10971859 | 0.78 | DRD2 (0.46) | HTR1AMAPTDRD2DRD4DRD3 | |
| SCHEMBL10972508 | 0.78 | DRD2 (0.53) | HTR1AMAPTDRD2DRD4DRD3 | |
| SCHEMBL10973150 | 0.78 | LMNA (0.48) | PARP1HTR1AMAPTDRD2DRD4 | |
| SCHEMBL10970861 | 0.76 | HTR1A (0.48) | PARP1HTR1ADRD2DRD4DRD3 | |
| SCHEMBL10971132 | 0.76 | HTR1A (0.58) | PARP1HTR1AMAPTDRD2DRD4 | |
| SCHEMBL10968918 | 0.76 | HTR1A (0.62) | HTR1AMAPTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164633-A2 | Indole derivatives | MERCK PATENT GmbH (DE) | 1985-12-18 | — | — | EP | disclosed |