Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972767 | 0.81 | FAAH (0.42) | FAAH | |
| SCHEMBL9685607 | 0.79 | FAAH (0.40) | FAAH | |
| SCHEMBL10976699 | 0.72 | MAPT (0.32) | — | |
| SCHEMBL16521881 | 0.71 | GAA (0.30) | — | |
| SCHEMBL14518643 | 0.69 | CYP1A2 (0.34) | — | |
| SCHEMBL25259222 | 0.68 | FAAH (0.41) | FAAH | |
| SCHEMBL23925244 | 0.68 | FAAH (0.41) | FAAH | |
| SCHEMBL11502461 | 0.67 | — | — | |
| SCHEMBL2664446 | 0.67 | — | — | |
| SCHEMBL14882997 | 0.67 | ALDH1A1 (0.44) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546104-A | Pyrazolopyridine cycloalkanones and process for their preparation | ICI AMERICAS INC. (US) | 1985-10-08 | — | — | US | disclosed |
| EP-0141608-A2 | Pyrazolopyridine cycloalkanone derivatives | ICI AMERICAS INC. (US) | 1985-05-15 | — | — | EP | disclosed |