Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | CTRC | Q99895 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627491 | 0.81 | FAAH (0.35) | FAAHPRSS1CTRCF2ALDH1A1 | |
| SCHEMBL10975436 | 0.79 | FAAH (0.45) | FAAH | |
| SCHEMBL370193 | 0.79 | FAAH (0.38) | FAAHPRSS1CTRCF2ALDH1A1 | |
| SCHEMBL10973802 | 0.76 | NOS1 (0.39) | FAAHPRSS1CTRCF2ALDH1A1 | |
| SCHEMBL16521881 | 0.74 | GAA (0.30) | — | |
| SCHEMBL15235664 | 0.74 | AKR1C4 (0.37) | ALDH1A1 | |
| SCHEMBL8169420 | 0.74 | ANPEP (0.47) | FAAH | |
| SCHEMBL10688107 | 0.73 | ALDH1A1 (0.39) | FAAHPRSS1CTRCF2ALDH1A1 | |
| Ethylene SCHEMBL8162249 | 0.72 | ANPEP (0.46) | FAAH | |
| SCHEMBL11502461 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809482-B2 | Silsesquioxane resins | DOW CORNING CORPORATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-8507179-B2 | Switchable antireflective coatings | DOW CORNING CORPORATION (US) | 2013-08-13 | — | — | US | disclosed |
| US-20110236835-A1 | Silsesquioxane Resins | DOW CORNING CORPORATION | 2011-09-29 | — | — | US | disclosed |
| US-20110236837-A1 | Switchable Antireflective Coatings | DOW SILICONES CORPORATION | 2011-09-29 | — | — | US | disclosed |
| US-20110233489-A1 | Silsesquioxane Resins | DOW CORNING CORPORATION | 2011-09-29 | — | — | US | disclosed |
| EP-0245053-B1 | HETEROCYCLIC FUSED TRICYCLIC COMPOUNDS | ICI AMERICAS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| US-5118688-A | TETRAHYDROPYRIDOQUINOLONE DERIVATIVES USEFUL AS ANXIOLYTIC AGENTS | ICI AMERICAS INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-4975435-A | Certain 1H-pyrrold[3,4-b]quinolin-1-one-9-amino-2,3-dihydro derivatives useful for treating anxiety | ICI AMERICAS INC. (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0245053-A1 | Heterocyclic fused tricyclic compounds | ICI AMERICAS INC. (US) | 1987-11-11 | — | — | EP | disclosed |
| US-4546104-A | Pyrazolopyridine cycloalkanones and process for their preparation | ICI AMERICAS INC. (US) | 1985-10-08 | — | — | US | disclosed |
| EP-0141608-A2 | Pyrazolopyridine cycloalkanone derivatives | ICI AMERICAS INC. (US) | 1985-05-15 | — | — | EP | disclosed |
| US-4463183-A | Method for preparing a prostacyclin intermediate | E. R. SQUIBB & SONS, INC. (US) | 1984-07-31 | — | — | US | disclosed |
| US-4456768-A | Chemical synthesis | THE UNIVERSITY OF CHICAGO (US) | 1984-06-26 | — | — | US | disclosed |
| US-4341710-A | Intermediates for 10,10-difluoroprostacyclins | E. R. SQUIBB & SONS, INC. (US) | 1982-07-27 | — | — | US | disclosed |
| US-4324730-A | Certain fluorine substituted PGI2 compounds | THE UNIVERSITY OF CHICAGO (US) | 1982-04-13 | — | — | US | disclosed |
| US-4317906-A | Method for preparing 10,10-difluoro prostacyclins | E. R. SQUIBB & SONS, INC. (US) | 1982-03-02 | — | — | US | disclosed |
| EP-0037422-A4 | FLUORO-SUBSTITUTED PROSTAGLANDINS AND PROSTACYCLINS. | UNIV CHICAGO (US) | 1982-01-26 | — | — | EP | disclosed |
| EP-0037422-A1 | FLUORO-SUBSTITUTED PROSTAGLANDINS AND PROSTACYCLINS | UNIVERSITY OF CHICAGO (US) | 1981-10-14 | — | — | EP | disclosed |
| WO-1981001002-A1 | FLUORO-SUBSTITUTED PROSTAGLANDINS AND PROSTACYCLINS | UNIV CHICAGO (US) | 1981-04-16 | — | — | WO | disclosed |