Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.46 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29229463 | 0.79 | RAB9A (0.67) | RAB9ASMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL29377227 | 0.76 | RAB9A (0.76) | RAB9ASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL9953323 | 0.76 | RAB9A (0.76) | RAB9ASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL7376294 | 0.75 | MAPT (0.49) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL30437013 | 0.75 | RAB9A (0.73) | RAB9ASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL29229519 | 0.74 | RAB9A (0.72) | RAB9ASMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL19710716 | 0.73 | KMT2A (0.70) | RAB9ASMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL30822644 | 0.73 | RAB9A (0.58) | RAB9ASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL16291434 | 0.71 | RAB9A (0.72) | RAB9ASMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL20886963 | 0.71 | RAB9A (1.00) | RAB9ASMN1; SMN2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056637-B1 | 4(3H)-QUINAZOLINONE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS | Ishikawa, Masayuki (JP) | 1985-07-24 | — | — | EP | disclosed |