Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 3/20 | 0.50 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907766 | 1.00 | NOS3 (0.50) | NOS3NOS2NCF1ASIC3SMPD3 | |
| Hydrochloric Acid SCHEMBL3335648 | 0.98 | NOS3 (0.48) | NOS3NOS2NCF1ASIC3SMPD3 | |
| 2-Aminopyridine SCHEMBL1279022 | 0.85 | NOS3 (0.55) | NOS3NOS2NCF1ASIC3ALDH1A1 | |
| SCHEMBL4271497 | 0.82 | NCF1 (0.52) | NCF1SMPD3ALDH1A1TP53CYP3A4 | |
| SCHEMBL4667703 | 0.80 | ALDH1A1 (0.43) | NOS3NOS2ASIC3ALDH1A1TP53 | |
| SCHEMBL28506084 | 0.79 | NOS3 (0.43) | NOS3NOS2NCF1ASIC3GRM4 | |
| SCHEMBL2252055 | 0.76 | NOS3 (0.45) | NOS3NOS2ASIC3ALDH1A1CYP3A4 | |
| SCHEMBL23104383 | 0.76 | HRH3 (0.59) | NOS3NOS2NOS1 | |
| SCHEMBL29736634 | 0.76 | HRH3 (0.59) | NOS3NOS2NOS1 | |
| SCHEMBL31415250 | 0.73 | CCR1 (0.50) | NOS3NOS2NCF1SMPD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112512792-B | Laminate and method for producing laminate | 东洋纺株式会社 | 2023-02-17 | — | — | CN | claimed |
| US-10639257-B2 | Composition for colouring keratin fibres | BEAUTY & BUSINESS S.P.A. (IT) | 2020-05-05 | — | — | US | claimed |
| US-20190117541-A1 | COMPOSITION FOR COLOURING KERATIN FIBRES | BEAUTY & BUSINESS S.P.A. (IT) | 2019-04-25 | — | — | US | claimed |
| EP-1598048-B1 | Composition for coloring of keratin fibres | KPSS KAO GMBH (DE) | 2008-08-13 | — | — | EP | claimed |
| US-20050209297-A1 | Pyrazole derivatives | PFIZER INC | 2005-09-22 | — | — | US | claimed |
| EP-4615839-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | Bristol-Myers Squibb Company (US) | 2025-09-17 | — | — | EP | disclosed |
| US-12337052-B2 | Hair treatment method that increases the bond density of damaged hair | BEAUTY & BUSINESS S.P.A. (IT) | 2025-06-24 | — | — | US | disclosed |
| EP-4548908-A1 | PERMANENT OXIDATIVE HAIR-COLOURING COMPOSITIONS | Beauty & Business SpA (IT) | 2025-05-07 | — | — | EP | disclosed |
| US-20250134788-A1 | PERMANENT OXIDATIVE HAIR-COLORING COMPOSITIONS | BEAUTY & BUSINESS S.P.A. (IT) | 2025-05-01 | — | — | US | disclosed |
| US-20240180886-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-06-06 | — | — | US | disclosed |
| WO-2024102794-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-16 | — | — | WO | disclosed |
| US-20240033199-A1 | HAIR TREATMENT METHOD THAT INCREASES THE BOND DENSITY OF DAMAGED HAIR | BEAUTY & BUSINESS S.P.A. (IT) | 2024-02-01 | — | — | US | disclosed |
| EP-0825985-B1 | A PROCESS FOR PREPARING PYRIDINE-2,6-DIAMINES | AKZO NOBEL NV (NL) | 1999-05-26 | — | — | EP | disclosed |
| EP-0825985-A1 | A PROCESS FOR PREPARING PYRIDINE-2,6-DIAMINES | Akzo Nobel N.V. (NL) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036607-A1 | A PROCESS FOR PREPARING PYRIDINE-2,6-DIAMINES | AKZO NOBEL N.V. (NL) | 1996-11-21 | — | — | WO | disclosed |
| US-4490533-A | Aminoalkyl pyridine derivatives | MERCK & CO., INC. (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0055179-A1 | Aminoalkyl pyridine derivatives | MERCK & CO. INC. (US) | 1982-06-30 | — | — | EP | disclosed |
| US-4207239-A | HYPOTENSIVE, ANTIPSYCHOTIC | THE UPJOHN COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-4206123-A | INTERMEDIATES FOR HYPOTENSIVES | MCCALL JOHN M (US) | 1980-06-03 | — | — | US | disclosed |
| US-4203988-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209297-A1 | Pyrazole derivatives | CDK1, CDK3, CDK5 | NOS3 639/4885NOS2 2607/4885NCF1 3598/4885 |
| US-20240180886-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | PTPN2, PTPN22, PTPN1 | NOS3 4303/4885NOS2 3281/4885NCF1 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.