⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974977 | 0.91 | — | — | |
| SCHEMBL10975127 | 0.84 | — | — | |
| SCHEMBL10975503 | 0.74 | QPCT (0.41) | — | |
| SCHEMBL10388136 | 0.67 | KDM4E (0.34) | — | |
| SCHEMBL5704114 | 0.66 | CYP2D6 (0.34) | — | |
| SCHEMBL5347005 | 0.66 | CYP2D6 (0.38) | — | |
| SCHEMBL7872949 | 0.65 | KDM4E (0.37) | — | |
| SCHEMBL5358112 | 0.64 | CYP2D6 (0.42) | — | |
| SCHEMBL10975797 | 0.63 | CYP2D6 (0.31) | — | |
| SCHEMBL710692 | 0.62 | CYP2D6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525475-A | Prevention of thrombolic disorder with imidazole derivatives and salts thereof | THOROGOOD PETER B (GB) | 1985-06-25 | — | — | US | disclosed |
| EP-0015002-B1 | 1-SUBSTITUTED IMIDAZOLES, AND SALTS THEREOF, A METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-04-18 | — | — | EP | disclosed |
| US-4328234-A | Imidazole derivatives and salts thereof and pharmaceutical formulations useful in thrombo-embolic disorders | BURROUGHS WELLCOME CO. (US) | 1982-05-04 | — | — | US | disclosed |
| EP-0015002-A1 | 1-substituted imidazoles, and salts thereof, a method for their preparation and pharmaceutical formulations thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-09-03 | — | — | EP | disclosed |