Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311655 | 0.83 | ALDH1A1 (0.50) | HSD17B10ALOX5LMNACYP2D6NPC1 | |
| SCHEMBL23509533 | 0.83 | ALOX5 (0.39) | HSD17B10ALOX5NPC1RAB9A | |
| SCHEMBL6423324 | 0.77 | CYP2D6 (0.60) | HSD17B10LMNACYP2D6POLBKDM4E | |
| SCHEMBL18922731 | 0.73 | ALOX5 (0.46) | ALOX5NPC1RAB9APOLBTDP1 | |
| Hydroquinone SCHEMBL6750226 | 0.73 | HSD17B10 (0.46) | HSD17B10LMNACYP2D6NPC1RAB9A | |
| SCHEMBL12417813 | 0.72 | ALOX5 (0.41) | ALOX5NPC1RAB9APOLBKDM4E | |
| SCHEMBL632678 | 0.72 | CHRM2 (0.42) | HSD17B10ALOX5CYP2D6NPC1RAB9A | |
| SCHEMBL7933210 | 0.71 | CA1 (0.46) | HTTKMT2ACA1CA2SLC6A2 | |
| SCHEMBL2181772 | 0.71 | CA1 (0.61) | LMNAPOLBMAPK1HTTKMT2A | |
| SCHEMBL873616 | 0.71 | CA1 (0.61) | LMNAPOLBMAPK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548752-A | FURAN COMPOSITIONS WITH PROPYLENE GLYCOL-USED FOR FIREPROOF POLYURETHANE FOAMS | QO CHEMICALS, INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4426460-A | Polyurethanes or isocyanurates from alkoxylated hydroxymethylfuran | QUAKER OATS COMPANY (US) | 1984-01-17 | — | — | US | disclosed |