Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074627 | 0.79 | IDO1 (0.44) | CYP1A2CYP3A4CYP2D6PRMT1TP53 | |
| SCHEMBL44259 | 0.79 | IDO1 (0.44) | CYP1A2CYP3A4CYP2D6PRMT1TP53 | |
| Benzyl Thiocyanate SCHEMBL129196 | 0.75 | MAOB (0.48) | CYP1A2IDO1NOS3NOS1NOS2 | |
| SCHEMBL28515 | 0.75 | CTSL (0.43) | CYP1A2CYP3A4CYP2D6PRMT1IDO1 | |
| SCHEMBL19514760 | 0.75 | CA12 (0.43) | CYP1A2CYP3A4CYP2D6PRMT1IDO1 | |
| SCHEMBL11384559 | 0.75 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2D6PRMT1IDO1 | |
| SCHEMBL9217746 | 0.75 | MAOB (0.44) | CYP1A2CYP3A4CYP2D6PRMT1IDO1 | |
| Benzyl Thiocyanate SCHEMBL27730692 | 0.75 | MAOB (0.48) | CYP1A2IDO1NOS3NOS1NOS2 | |
| SCHEMBL1679996 | 0.75 | IDO1 (0.41) | CYP1A2CYP3A4CYP2D6PRMT1IDO1 | |
| SCHEMBL11375999 | 0.75 | MAOB (0.41) | CYP1A2CYP3A4CYP2D6PRMT1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536391-A | REACTING A PLASMIN HEAVY CHAIN WITH UROKINASE IN THE PRESENCE OF A COUPLING AGENT | OTSUKA PHARMACEUTICAL CO. (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0109653-A2 | Process for preparing urokinase complex | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-05-30 | — | — | EP | disclosed |