SCHEMBL44259

SCHEMBL44259

C(#CSCc1ccccc1)SCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
MAOB P27338 3/20 0.43
POLB P06746 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CALM1 P0DP23 1/20 0.43
MAOA P21397 2/20 0.42
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
PRMT1 Q99873 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9217746 0.90 MAOB (0.44) IDO1NOS3NOS1NOS2MAOB
SCHEMBL23138287 0.89 IDO1 (0.38) IDO1NOS3NOS1NOS2MAOB
SCHEMBL28359780 0.84 PAM (0.55) IDO1NOS3NOS1NOS2MAOB
SCHEMBL2074627 0.83 IDO1 (0.44) IDO1NOS3NOS1NOS2MAOB
SCHEMBL28420190 0.82 TP53 (0.41) IDO1NOS3NOS1NOS2MAOB
SCHEMBL28902312 0.80 CYP2D6 (0.44) IDO1NOS3NOS1NOS2MAOB
SCHEMBL23088675 0.80 EGFR (0.39) IDO1NOS3NOS1NOS2MAOB
SCHEMBL1679996 0.79 IDO1 (0.41) IDO1NOS3NOS1NOS2MAOB
SCHEMBL10978005 0.79 CYP1A2 (0.42) IDO1NOS3NOS1NOS2MAOB
SCHEMBL11384559 0.79 CYP1A2 (0.42) IDO1NOS3NOS1NOS2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133616-A1 CONJUGATED POLYMER NANOPARTICLE BIOSENSORS STREAM BIO LTD (GB) 2025-06-26 WO claimed
US-8980473-B2 Anode and battery SONY CORPORATION (JP) 2015-03-17 US claimed
US-8609258-B2 Light emitting devices and compositions NITTO DENKO CORPORATION (JP) 2013-12-17 US claimed
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2012-12-06 US claimed
US-20120269736-A1 MICELLAR COMPOSITIONS FOR USE IN BIOLOGICAL APPLICATIONS KING'S COLLEGE LONDON (GB) 2012-10-25 US claimed
US-8179589-B2 Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. (US) 2012-05-15 US claimed
WO-2011039535-A2 MICELLAR COMPOSITIONS FOR USE IN BIOLOGICAL APPLICATIONS KING'S COLLEGE LONDON (GB) 2011-04-07 WO claimed
US-20100301280-A1 METHODS AND COMPOSITIONS FOR IMPROVED ELECTROPHORETIC DISPLAY PERFORMANCE SIPIX IMAGING INC. 2010-12-02 US claimed
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-03-12 US claimed
WO-2009006550-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS NITTO DENKO CORPORATION (JP) 2009-01-08 WO claimed
EP-1529242-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER Sipix Imaging, Inc. (US) 2005-05-11 EP claimed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US claimed
WO-2004010206-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER SIPIX IMAGING, INC. (US) 2004-01-29 WO claimed
WO-2025133616-A1 CONJUGATED POLYMER NANOPARTICLE BIOSENSORS STREAM BIO LTD (GB) 2025-06-26 WO disclosed
US-10786683-B2 Light-emitting devices for wound healing NITTO DENKO CORPORATION (JP) 2020-09-29 US disclosed
US-9978953-B2 Substituted biphenyl compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2018-05-22 US disclosed
US-20050007648-A1 Methods and compositions for improved electrophoretic display performance E INK CORPORATION 2005-01-13 US disclosed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed
US-4886627-A Conductive structures in polymers VEB METALLURGIEELEKTRONIK LEIPZIG (DD) 1989-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066234-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS MAP1LC3A, MAP1LC3C, CRY1 IDO1 273/4885NOS3 2115/4885NOS1 1729/4885
US-20120305895-A1 LIGHT EMITTING DEVICES AND COMPOSITIONS ILK, CRY1, IK IDO1 393/4885NOS3 2782/4885NOS1 1214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.