Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074627 | 0.84 | IDO1 (0.44) | CTSLCTSBCYP2C19IDO1NOS3 | |
| SCHEMBL44259 | 0.79 | IDO1 (0.44) | CTSLCTSBCYP2C19IDO1NOS3 | |
| SCHEMBL4711079 | 0.78 | CYP1A2 (0.45) | CYP2C19NOS1MAOBHSD17B10MAOA | |
| SCHEMBL3633725 | 0.76 | IDO1 (0.45) | IDO1MAOBMAOACA12CA1 | |
| SCHEMBL3634433 | 0.76 | IDO1 (0.45) | CYP2C19IDO1MAOBMAOAALDH1A1 | |
| SCHEMBL11103439 | 0.76 | CTSL (0.41) | CTSLCTSBCYP2C19IDO1NOS3 | |
| SCHEMBL9217746 | 0.75 | MAOB (0.44) | CTSLCTSBCYP2C19IDO1NOS3 | |
| SCHEMBL11384559 | 0.75 | CYP1A2 (0.42) | CTSLCTSBCYP2C19IDO1NOS3 | |
| SCHEMBL1679996 | 0.75 | IDO1 (0.41) | CTSLCTSBCYP2C19IDO1NOS3 | |
| Benzyl Thiocyanate SCHEMBL129196 | 0.75 | MAOB (0.48) | CTSLCTSBIDO1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | claimed |
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-104877127-A | Eight-armed polyethylene glycol derivative, preparation method and related biological substance modified by derivative | XIAMEN SINOPEG BIOTECH CO LTD | 2015-09-02 | — | — | CN | claimed |
| CN-104725628-A | Single functional branched polyethylene glycol containing degradable radical, preparation method and biorelevant substance of single functional branched polyethylene glycol | XIAMEN SINOPEG BIOTECH CO LTD | 2015-06-24 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530413-A | Biologically related substances modified by multifunctional H-type polyethylene glycol derivative | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| EP-1514542-B1 | Medicinal composition comprising Tacrine or Donepezil for improving brain function. | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | claimed |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | claimed |
| US-6002016-A | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-14 | — | — | US | claimed |
| WO-1998042698-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | NOVARTIS AG (CH) | 1998-10-01 | — | — | WO | claimed |
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | claimed |
| EP-0595125-B1 | Substituted aza(cyclo) alkanes and their use as pesticides | BAYER AG (DE) | 1996-05-15 | — | — | EP | claimed |
| US-5461069-A | Insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-24 | — | — | US | claimed |
| EP-0595125-A1 | Substituted aza(cyclo) alkanes and their use as pesticides | BAYER AG (DE) | 1994-05-04 | — | — | EP | claimed |
| EP-0292822-B1 | Substituted nitroalkenes | BAYER AG (DE) | 1994-01-12 | — | — | EP | claimed |
| US-4968695-A | NEMATOCIDES, LARVICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | claimed |
| EP-0292822-A2 | Substituted nitroalkenes | BAYER AG (DE) | 1988-11-30 | — | — | EP | claimed |
| US-4150227-A | Process for the production of basic substituted alkyl theophylline | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-04-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | MB, ACHE, ADORA2B | CTSL 2448/4885CTSB 1739/4885CYP2C19 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.