Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961611 | 0.81 | CYP1A2 (0.33) | CYP1A2HSD17B10 | |
| SCHEMBL11502939 | 0.81 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL11503037 | 0.81 | HSD17B10 (0.31) | LMNAKMT2AHSD17B10 | |
| SCHEMBL11502712 | 0.80 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL11502526 | 0.80 | CYP1A2 (0.32) | CYP1A2HSD17B10 | |
| SCHEMBL11502804 | 0.80 | HSD17B10 (0.33) | LMNAKMT2AALDH1A1HSD17B10 | |
| SCHEMBL11485330 | 0.78 | LMNA (0.33) | LMNAKMT2ACYP1A2 | |
| SCHEMBL10607988 | 0.77 | PTGES (0.49) | LMNAKMT2AHSD17B10 | |
| SCHEMBL11502518 | 0.77 | — | — | |
| SCHEMBL11615205 | 0.76 | PTGES (0.48) | LMNAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049814-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-01-09 | — | — | EP | disclosed |
| US-4362725-A | ANTIBIOTICS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-12-07 | — | — | US | disclosed |
| EP-0049814-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1982-04-21 | — | — | EP | disclosed |