Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10607988 | 0.98 | PTGES (0.49) | PTGESHSD17B10HTTGHSRLMNA | |
| SCHEMBL11617589 | 0.89 | PTGES (0.40) | PTGESHSD17B10HTTGHSR | |
| SCHEMBL11615496 | 0.88 | GHSR (0.40) | PTGESHSD17B10HTTGHSR | |
| SCHEMBL11668152 | 0.86 | GHSR (0.41) | PTGESHSD17B10GHSR | |
| SCHEMBL11038602 | 0.82 | PTGES (0.36) | PTGES | |
| SCHEMBL10667828 | 0.81 | PTGES (0.33) | PTGES | |
| SCHEMBL11616582 | 0.80 | PTGES (0.41) | PTGESHSD17B10 | |
| SCHEMBL11617739 | 0.78 | PTGES (0.39) | PTGESHSD17B10HTTKMT2A | |
| SCHEMBL10979892 | 0.76 | LMNA (0.33) | HSD17B10LMNAKMT2A | |
| SCHEMBL10403870 | 0.75 | ALDH1A1 (0.37) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101656-A | 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |