Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973770 | 0.89 | CNR1 (0.56) | CNR1CNR2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10977573 | 0.88 | CNR1 (0.55) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL10972776 | 0.87 | CNR1 (0.54) | CNR1CNR2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11340568 | 0.84 | CNR1 (0.52) | CNR1CNR2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL10977927 | 0.84 | ALDH1A1 (0.52) | CNR1CNR2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11075891 | 0.77 | CNR1 (0.65) | CNR1CNR2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL10972699 | 0.76 | CNR1 (0.67) | CNR1CNR2ALDH1A1MAPTKMT2A | |
| SCHEMBL11080762 | 0.76 | CNR1 (0.67) | CNR1CNR2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11071848 | 0.76 | CNR1 (0.57) | CNR1CNR2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL10974453 | 0.76 | CNR1 (0.69) | CNR1CNR2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056637-B1 | 4(3H)-QUINAZOLINONE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS | Ishikawa, Masayuki (JP) | 1985-07-24 | — | — | EP | disclosed |
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | disclosed |