Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SPR | P35270 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510829 | 0.81 | ADAM17 (0.59) | ALDH1A1HPGDKDM4EMAPTBLM | |
| SCHEMBL9080492 | 0.77 | TRPV1 (0.53) | KDM4ECYP3A4TRPV1PTGS1PTGS2 | |
| SCHEMBL23612236 | 0.77 | NPSR1 (0.54) | ALDH1A1NPSR1LMNAHPGDTSHR | |
| SCHEMBL5834265 | 0.77 | HTR2C (0.51) | ALDH1A1NPSR1LMNAHPGDTSHR | |
| SCHEMBL10903029 | 0.75 | TRPV1 (0.45) | ALDH1A1NPSR1LMNAHPGDKDM4E | |
| SCHEMBL1723364 | 0.75 | NPSR1 (0.72) | ALDH1A1NPSR1LMNAHPGDTSHR | |
| SCHEMBL19367461 | 0.74 | SPR (0.48) | ALDH1A1NPSR1LMNAHPGDTSHR | |
| SCHEMBL3203835 | 0.73 | APEX1 (0.51) | ALDH1A1HPGDTSHRKDM4ETDP1 | |
| SCHEMBL30233531 | 0.73 | NPSR1 (0.56) | ALDH1A1NPSR1LMNAHPGDTSHR | |
| SCHEMBL25024359 | 0.73 | NPSR1 (0.56) | ALDH1A1NPSR1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057631-B1 | ((INDOL-3-YL)-3-AMINO-2 PROPIONYLOXY)-2-ACETIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | PANMEDICA (FR) | 1985-02-20 | — | — | EP | claimed |