Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179874 | 0.82 | TRPV1 (0.66) | TRPV1BCHEACHEKDM4ECYP3A4 | |
| SCHEMBL8185580 | 0.81 | TRPV1 (0.48) | TRPV1HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL10980190 | 0.77 | ALDH1A1 (0.55) | TRPV1KDM4ECYP3A4PTGS1PTGS2 | |
| SCHEMBL6441244 | 0.74 | TRPV1 (0.58) | TRPV1KDM4ECYP3A4PTGS1PTGS2 | |
| SCHEMBL9540825 | 0.73 | TRPV1 (0.56) | TRPV1ACHEKDM4ECYP3A4PTGS1 | |
| SCHEMBL27508914 | 0.72 | MTNR1A (0.59) | TRPV1KDM4E | |
| SCHEMBL10276923 | 0.71 | HDAC1 (0.60) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL8171402 | 0.71 | MAPT (0.64) | HDAC1KDM4E | |
| SCHEMBL137348 | 0.71 | HDAC4 (0.85) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL6669511 | 0.71 | HDAC4 (0.85) | HDAC1HDAC3HDAC2HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559143-A | Serotonin 5HT1A agonistic method | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |