Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20998690 | 0.79 | CRHBP (0.55) | CRHBPCRHR2CYP1A2CYP2C19MAOA | |
| SCHEMBL10980250 | 0.78 | CRHBP (0.53) | CRHBPCRHR2ADORA2ACYP1A2CYP3A4 | |
| SCHEMBL12374084 | 0.78 | ADORA2A (0.44) | ADORA2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12620334 | 0.75 | PIN1 (0.60) | ADORA2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3207306 | 0.75 | CRHBP (0.43) | CRHBPCRHR2CYP1A2CYP2C19F10 | |
| SCHEMBL29193018 | 0.75 | RAB9A (0.51) | CRHBPCRHR2F10RAB9AKMT2A | |
| SCHEMBL1309128 | 0.74 | P2RY1 (0.36) | CRHBPCRHR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16670718 | 0.73 | BTK (0.53) | CRHBPCRHR2F10RAB9AKMT2A | |
| SCHEMBL16234979 | 0.72 | CRHBP (0.41) | CRHBPCRHR2CYP3A4TSHRMERTK | |
| SCHEMBL29364510 | 0.72 | CRHBP (0.41) | CRHBPCRHR2CYP3A4TSHRMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4504483-A | Fluorine substituted pyridine methyl esters and insecticidal and acaricidal compositions thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-12 | — | — | US | disclosed |
| US-4499275-A | PESTICIDES; INSECTICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| US-4393213-A | Process for producing 6-phenoxypicolinic aldehydes | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1983-07-12 | — | — | US | disclosed |