Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 18/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 18/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 18/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060887 | 0.89 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CNISCHHTR1A | |
| SCHEMBL10976651 | 0.88 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL3058505 | 0.88 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CNISCHHTR1A | |
| SCHEMBL11224297 | 0.82 | NISCH (0.54) | ADRA2AADRA2BADRA2CNISCHHTR1A | |
| Hydrochloric Acid SCHEMBL9654753 | 0.81 | NISCH (0.53) | ADRA2AADRA2BADRA2CNISCHHTR1A | |
| SCHEMBL11370259 | 0.80 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CNISCHHTR1A | |
| SCHEMBL1397851 | 0.77 | ADRA2B (0.57) | ADRA2AADRA2BADRA2CNISCHHTR1A | |
| SCHEMBL3961615 | 0.75 | NISCH (0.52) | ADRA2AADRA2BADRA2CNISCHHTR1A | |
| SCHEMBL18106785 | 0.75 | TDP1 (0.53) | TDP1 | |
| SCHEMBL3065600 | 0.74 | ADRA2B (0.48) | ADRA2AADRA2BADRA2CNISCHHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4523020-A | USEFUL FOR TREATMENT OF DIARRHEA AND AS ANALGESICS | G. D. SEARLE & CO. (US) | 1985-06-11 | — | — | US | disclosed |