Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 19/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 19/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 19/20 | 0.52 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981645 | 0.88 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL3060887 | 0.86 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL10979198 | 0.81 | NISCH (0.43) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| SCHEMBL3058505 | 0.77 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL546009 | 0.75 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| SCHEMBL11352087 | 0.73 | NISCH (0.52) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| SCHEMBL545961 | 0.73 | NISCH (0.52) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| SCHEMBL3065600 | 0.72 | ADRA2B (0.48) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL27797929 | 0.72 | NISCH (0.59) | ADRA2AADRA2BADRA2CNISCHMAOA | |
| Hydrochloric Acid SCHEMBL3071166 | 0.71 | NISCH (0.57) | ADRA2AADRA2BADRA2CNISCHMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4523020-A | USEFUL FOR TREATMENT OF DIARRHEA AND AS ANALGESICS | G. D. SEARLE & CO. (US) | 1985-06-11 | — | — | US | disclosed |