SCHEMBL10982129

SCHEMBL10982129

C=CCOC(=O)c1ccc(N)cc1CCC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
HSD17B10 Q99714 3/20 0.51
TSHR P16473 2/20 0.51
CYP3A4 P08684 3/20 0.50
CYP1A2 P05177 3/20 0.41
CYP2D6 P10635 1/20 0.41
SCN1A P35498 1/20 0.41
SCN2A Q99250 1/20 0.41
SCN3A Q9NY46 1/20 0.41
MAOA P21397 2/20 0.40
CHRM2 P08172 1/20 0.40
CHRM3 P20309 1/20 0.40
HTR2C P28335 1/20 0.40
CHRNA4 P43681 1/20 0.40
HTR3A P46098 1/20 0.40
KCNH2 Q12809 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11032684 0.91 TSHR (0.48) ALDH1A1HSD17B10TSHRCYP3A4CYP1A2
SCHEMBL8191128 0.85 LMNA (0.51) ALDH1A1HSD17B10TSHRCYP3A4CYP1A2
SCHEMBL10336950 0.84 HSD17B10 (0.55) ALDH1A1HSD17B10TSHRCYP3A4CYP1A2
SCHEMBL5102454 0.82 CYP3A4 (0.64) ALDH1A1HSD17B10TSHRCYP3A4CYP1A2
SCHEMBL3945760 0.81 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRCYP3A4CYP1A2
SCHEMBL27645830 0.81 CYP3A4 (0.68) ALDH1A1HSD17B10TSHRCYP3A4SCN1A
SCHEMBL14547866 0.81 GAA (0.58) ALDH1A1HSD17B10TSHRCYP1A2CYP2D6
Hydrochloric Acid SCHEMBL4722723 0.80 GAA (0.57) ALDH1A1HSD17B10TSHRCYP1A2CYP2D6
SCHEMBL8106325 0.80 GAA (0.57) ALDH1A1HSD17B10TSHRCYP3A4GAA
SCHEMBL5095303 0.78 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRCYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4529602-A Sulfodehydroabietic acid compound TANABE SEIYAKU CO., LTD. (JP) 1985-07-16 US claimed