Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10982129 | 0.91 | ALDH1A1 (0.51) | TSHRALDH1A1HSD17B10CYP3A4NPC1 | |
| SCHEMBL3859566 | 0.83 | CYP3A4 (0.62) | TSHRALDH1A1HSD17B10CYP3A4THRA | |
| SCHEMBL9307300 | 0.82 | LMNA (0.49) | TSHRALDH1A1HSD17B10CYP3A4NPC1 | |
| SCHEMBL10336950 | 0.81 | HSD17B10 (0.55) | TSHRALDH1A1HSD17B10CYP3A4MAPT | |
| SCHEMBL5102454 | 0.79 | CYP3A4 (0.64) | TSHRALDH1A1HSD17B10CYP3A4MAPT | |
| SCHEMBL27666844 | 0.79 | CYP3A4 (0.64) | TSHRALDH1A1HSD17B10CYP3A4MAPT | |
| SCHEMBL3945760 | 0.78 | ALDH1A1 (0.55) | TSHRALDH1A1HSD17B10CYP3A4NPC1 | |
| SCHEMBL2481632 | 0.78 | GABRP (0.54) | ALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL8191128 | 0.76 | LMNA (0.51) | TSHRALDH1A1HSD17B10CYP3A4NPC1 | |
| SCHEMBL9068637 | 0.76 | PPARA (0.54) | ALDH1A1CYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529602-A | Sulfodehydroabietic acid compound | TANABE SEIYAKU CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |
| EP-0078152-A1 | Salts of sulfodehydroabietic acid and treatment of gastro-intestinal diseases | Tanabe Seiyaku Co., Ltd. (JP) | 1983-05-04 | — | — | EP | disclosed |