Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 3/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484599 | 0.88 | LMNA (0.56) | FFAR1FFAR4ALDH1A1MEN1LMNA | |
| SCHEMBL5674809 | 0.84 | TDP1 (0.53) | ATMTDP1ALDH1A1MEN1LMNA | |
| SCHEMBL2729354 | 0.84 | TDP1 (0.53) | ATMTDP1ALDH1A1MEN1LMNA | |
| Methane SCHEMBL28528368 | 0.83 | TDP1 (0.51) | ATMTDP1ALDH1A1MEN1LMNA | |
| SCHEMBL22338991 | 0.82 | ATM (0.45) | ATMTDP1ALDH1A1MEN1LMNA | |
| SCHEMBL16246163 | 0.82 | ATM (0.55) | ATMTDP1ALDH1A1MEN1LMNA | |
| SCHEMBL8790409 | 0.81 | TSHR (0.55) | FFAR1FFAR4ALDH1A1KMT2AGSTP1 | |
| SCHEMBL510443 | 0.81 | GSTP1 (0.46) | FFAR1FFAR4ALDH1A1GSTP1GSTM2 | |
| SCHEMBL23413210 | 0.80 | TDP1 (0.56) | ATMTDP1ALDH1A1LMNACA1 | |
| SCHEMBL29780553 | 0.80 | TDP1 (0.56) | ATMTDP1ALDH1A1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077662-B1 | PREPARATION OF NITROARYLACETIC ACID ESTERS AND DERIVATIVES THEREOF | ETHYL CORPORATION (US) | 1985-10-02 | — | — | EP | claimed |
| EP-0077662-A1 | Preparation of nitroarylacetic acid esters and derivatives thereof | ETHYL CORPORATION (US) | 1983-04-27 | — | — | EP | claimed |