Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729354 | 0.98 | TDP1 (0.53) | TDP1ATMCYP1A2LMNAKDM4E | |
| SCHEMBL5674809 | 0.98 | TDP1 (0.53) | TDP1ATMCYP1A2LMNAKDM4E | |
| SCHEMBL2648717 | 0.85 | LMNA (0.53) | TDP1CYP1A2LMNAKDM4EMAPT | |
| SCHEMBL2656422 | 0.85 | LMNA (0.53) | TDP1CYP1A2LMNAKDM4EMAPT | |
| SCHEMBL29100216 | 0.84 | ATM (0.51) | TDP1ATMCYP1A2LMNAMAPT | |
| SCHEMBL29902892 | 0.84 | ATM (0.51) | TDP1ATMLMNAKDM4EMAPT | |
| SCHEMBL28847424 | 0.84 | ATM (0.51) | TDP1ATMLMNAKDM4EMAPT | |
| SCHEMBL1865824 | 0.83 | CASP6 (0.55) | TDP1CYP1A2LMNAKDM4EMAPT | |
| SCHEMBL10982297 | 0.83 | ATM (0.50) | TDP1ATMLMNAMAPTGAA | |
| SCHEMBL4131823 | 0.80 | ATM (0.47) | TDP1ATMLMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225657-A | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2021-01-15 | — | — | CN | claimed |
| CN-112225657-B | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-112225657-A | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2021-01-15 | — | — | CN | disclosed |