Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.59 |
| ▸ | BRAF | P15056 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983993 | 0.86 | GLO1 (0.66) | GLO1ALDH1A1CA1CA2CA4 | |
| SCHEMBL10896757 | 0.83 | GLO1 (0.61) | GLO1ALDH1A1CA1CA2CA4 | |
| SCHEMBL10896764 | 0.83 | GLO1 (0.61) | GLO1ALDH1A1CA1CA2CA4 | |
| SCHEMBL11564904 | 0.81 | GLO1 (0.63) | GLO1ALDH1A1CA1CA2CA4 | |
| SCHEMBL10985885 | 0.80 | LMNA (0.55) | GLO1BRAFALDH1A1LMNANPC1 | |
| SCHEMBL10988257 | 0.77 | GLO1 (0.51) | GLO1ALDH1A1CA1CA2CA4 | |
| SCHEMBL10989985 | 0.76 | GLO1 (0.61) | GLO1ALDH1A1CA1CA2CA4 | |
| SCHEMBL8028846 | 0.75 | GLO1 (1.00) | GLO1ALDH1A1CA1CA2CA4 | |
| SCHEMBL10481063 | 0.74 | GLO1 (0.75) | GLO1ALDH1A1CA1CA2CA4 | |
| SCHEMBL10481060 | 0.74 | GLO1 (0.75) | GLO1ALDH1A1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551467-A | Vasodilating cyanoalkyl esters of 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |
| US-4179500-A | 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |