Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10896764 | 0.81 | GLO1 (0.61) | GLO1RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL10896757 | 0.81 | GLO1 (0.61) | GLO1RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL10983993 | 0.80 | GLO1 (0.66) | GLO1RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL10983080 | 0.77 | GLO1 (0.59) | GLO1MAPTALDH1A1NPC1L3MBTL1 | |
| SCHEMBL9433401 | 0.74 | MAPT (0.64) | GLO1RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL9434245 | 0.74 | MAPT (0.64) | GLO1RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL11564904 | 0.73 | GLO1 (0.63) | GLO1MAPTALDH1A1NPC1CYP1A2 | |
| SCHEMBL9433707 | 0.72 | GLO1 (0.64) | GLO1RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL9433701 | 0.72 | GLO1 (0.64) | GLO1RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL10982646 | 0.70 | GLO1 (0.59) | GLO1MAPTALDH1A1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551467-A | Vasodilating cyanoalkyl esters of 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |
| US-4179500-A | 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |