Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | IGFBP3 | P17936 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988926 | 0.88 | GRM2 (0.49) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL3590415 | 0.87 | TSPO (0.59) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL31339992 | 0.87 | TSPO (0.59) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL10990018 | 0.86 | KMT2A (0.50) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL10994746 | 0.77 | CSNK2A2 (0.55) | KMT2ACNR1 | |
| SCHEMBL10993917 | 0.75 | GRM2 (0.62) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL10987170 | 0.74 | TSPO (0.58) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL15850566 | 0.74 | TSPO (0.61) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL10986804 | 0.74 | CNR1 (0.43) | TSPOKMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL3035741 | 0.73 | KMT2A (0.46) | TSPOKMT2AMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499094-A | PREVENTION OF RESPIRATORY, UROGENITAL, CARDIOVASCULAR AND IMMUNOLOGICAL DISORDERS WHEN USING FOR BENZDIAPINES | PHARMUKA LABORATOIRES (FR) | 1985-02-12 | — | — | US | disclosed |