Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | TSPO | P30536 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590415 | 0.85 | TSPO (0.59) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL31339992 | 0.85 | TSPO (0.59) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL3039437 | 0.81 | TSPO (0.52) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL3039772 | 0.81 | TSPO (0.52) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL3041620 | 0.81 | TSPO (0.52) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL3036447 | 0.78 | TSPO (0.79) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL3040202 | 0.78 | TSPO (0.79) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL3035730 | 0.78 | TSPO (0.79) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL3043587 | 0.78 | RXFP1 (0.41) | KMT2ATSPOMEN1ALDH1A1NPSR1 | |
| SCHEMBL3041673 | 0.77 | KMT2A (0.39) | KMT2ATSPOMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110064662-A1 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY | RIKEN (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20110064662-A1 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY | RIKEN (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20110064662-A1 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY | RIKEN (JP) | 2011-03-17 | — | — | US | disclosed |
| EP-2228363-A1 | KIT FOR USE IN PRODUCTION OF MOLECULAR PROBE FOR PET DRUG SCREENING | Riken (JP) | 2010-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064662-A1 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY | KIT, TPX2, RUNX1 | KMT2A 2122/4885TSPO 241/4885MEN1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.