Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | IGFBP3 | P17936 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31339992 | 1.00 | TSPO (0.59) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL10984073 | 0.87 | TSPO (0.47) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL10987170 | 0.87 | TSPO (0.58) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL15850566 | 0.87 | TSPO (0.61) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL10990018 | 0.85 | KMT2A (0.50) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL3035741 | 0.85 | KMT2A (0.46) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL3434531 | 0.83 | TSPO (0.58) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL8470659 | 0.82 | TSPO (0.59) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL117174 | 0.82 | ADORA2A (0.48) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL10982335 | 0.82 | CNR1 (0.56) | TSPOKMT2AMEN1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429161-A | Synthesis of PET imaging agent prosome isoquinoline methanamide derivant | CHANGSHU INST TECHNOLOGY (CN) | 2009-05-13 | — | — | CN | claimed |
| US-20250049839-A1 | COMPOSITIONS AND METHODS FOR TARGETING CELLS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-02-13 | — | — | US | disclosed |
| US-12161663-B2 | Compositions and methods for targeting cells | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2024-12-10 | — | — | US | disclosed |
| US-11608483-B2 | Inverted culture plate system for cellular co-culture | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-03-21 | — | — | US | disclosed |
| CN-113321616-A | Method for synthesizing precursor of Alzheimer's disease beta-amyloid protein deposition imaging drug | 江苏华益科技有限公司 | 2021-08-31 | — | — | CN | disclosed |
| US-20210046105-A1 | COMPOSITIONS AND METHODS FOR TARGETING CELLS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-02-18 | — | — | US | disclosed |
| WO-2019191650-A1 | COMPOSITIONS AND METHODS FOR TARGETING CELLS | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2019-10-03 | — | — | WO | disclosed |
| US-20190249126-A1 | INVERTED CULTURE PLATE SYSTEM FOR CELLULAR CO-CULTURE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-08-15 | — | — | US | disclosed |
| US-9212167-B2 | Mitochondrial targeted stimulators of apoptosis | THE ROCKEFELLER UNIVERSITY (US) | 2015-12-15 | — | — | US | disclosed |
| US-9212167-B2 | Mitochondrial targeted stimulators of apoptosis | THE ROCKEFELLER UNIVERSITY (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2008023357-A1 | HETEROCYCLIC DERIVATIVES BINDING TO THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR (PBR) | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2008-02-28 | — | — | WO | disclosed |
| US-20070059230-A1 | Process | GLAXO GROUP LIMITED | 2007-03-15 | — | — | US | disclosed |
| EP-1429783-A4 | MULTI-USE MULTIMODAL IMAGING CHELATES | UNIV TEXAS TECH (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1663868-A2 | PROCESS FOR PREPARING RADIOLABELLED COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005014479-A2 | PROCESS FOR PREPARING RADIOLABELED COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |
| EP-1429783-A2 | MULTI-USE MULTIMODAL IMAGING CHELATES | TEXAS TECH UNIVERSITY (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003020701-A9 | MULTI-USE MULTIMODAL IMAGING CHELATES | UNIV TEXAS TECH (US) | 2003-09-12 | — | — | WO | disclosed |
| US-20030129579-A1 | Formed from 1,4,7,10 tetraazacyclododecane having varying chelating ions, phosphoester chains, and light harvesting moieties. | VANDERBILT UNIVERSITY | 2003-07-10 | — | — | US | disclosed |
| WO-2003020701-A2 | MULTI-USE MULTIMODAL IMAGING CHELATES | TEXAS TECH UNIVERSITY (US) | 2003-03-13 | — | — | WO | disclosed |
| US-4499094-A | PREVENTION OF RESPIRATORY, UROGENITAL, CARDIOVASCULAR AND IMMUNOLOGICAL DISORDERS WHEN USING FOR BENZDIAPINES | PHARMUKA LABORATOIRES (FR) | 1985-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12161663-B2 | Compositions and methods for targeting cells | CD47, CD44, CX3CR1 | TSPO 33/4885KMT2A 3252/4885MEN1 2860/4885 |
| US-20250049839-A1 | COMPOSITIONS AND METHODS FOR TARGETING CELLS | CD47, CD44, CX3CR1 | TSPO 33/4885KMT2A 3252/4885MEN1 2860/4885 |
| US-20030129579-A1 | Formed from 1,4,7,10 tetraazacyclododecane having varying chelating ions, phosphoester chains, and light harvesting moieties. | PCNA, CLTC, PHOSPHO1 | TSPO 423/4885KMT2A 2159/4885MEN1 181/4885 |
| US-20210046105-A1 | COMPOSITIONS AND METHODS FOR TARGETING CELLS | CD47, CD44, CX3CR1 | TSPO 33/4885KMT2A 3252/4885MEN1 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.