Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | EYA2 | O00167 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847204 | 0.91 | TDP1 (0.44) | ALOX15TSHRCYP2C19TDP1HIF1A | |
| SCHEMBL10985490 | 0.89 | TDP1 (0.41) | ALOX15TSHRCYP2C19TDP1HIF1A | |
| SCHEMBL10984383 | 0.88 | SMN1; SMN2 (0.38) | ALOX15TSHRCYP2C19HIF1AMEN1 | |
| SCHEMBL10985506 | 0.84 | ALOX15 (0.36) | ALOX15TSHRCYP2C19TDP1HIF1A | |
| SCHEMBL17075274 | 0.80 | TSHR (0.40) | ALOX15TSHRCYP2C19TDP1HIF1A | |
| SCHEMBL10986824 | 0.77 | SMN1; SMN2 (0.37) | MEN1KMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL3132717 | 0.76 | HTT (0.53) | ALOX15TSHRCYP2C19HIF1AMEN1 | |
| SCHEMBL10984140 | 0.75 | ALOX15 (0.35) | ALOX15TSHRCYP2C19TDP1HIF1A | |
| SCHEMBL18493237 | 0.75 | ALDH1A1 (0.44) | TSHRCYP2C19TDP1MEN1KMT2A | |
| SCHEMBL641321 | 0.75 | TDP1 (0.49) | ALOX15TSHRCYP2C19TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4543216-A | REACTING A VINYL BENZYL HALIDE WITH AN AMINO ACID OR AMINO SULFONIC ACID | NIPPON PAINT CO., LTD. (JP) | 1985-09-24 | — | — | US | disclosed |
| US-4452746-A | TO MODIFY PROPERTIES OF HIGH MOLECULAR WEIGHT COMPOUNDS | NIPPON PAINT CO., LTD. (JP) | 1984-06-05 | — | — | US | disclosed |