Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | ACR | P10323 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847204 | 0.88 | TDP1 (0.44) | TSHRALOX15CYP2C19HIF1ATDP1 | |
| SCHEMBL10985490 | 0.84 | TDP1 (0.41) | TSHRALOX15CYP2C19HIF1ATDP1 | |
| SCHEMBL10984140 | 0.82 | ALOX15 (0.35) | TSHRALOX15CYP2C19HIF1ATDP1 | |
| SCHEMBL10984905 | 0.80 | ALOX15 (0.38) | TSHRALOX15CYP2C19HIF1ATDP1 | |
| SCHEMBL10985506 | 0.75 | ALOX15 (0.36) | TSHRALOX15CYP2C19HIF1ATDP1 | |
| SCHEMBL10984657 | 0.75 | SMPD2 (0.43) | KMT2AKEAP1 | |
| SCHEMBL10991548 | 0.74 | BCHE (0.34) | TDP1KMT2A | |
| SCHEMBL10985617 | 0.73 | SMPD2 (0.39) | CYP2C19KEAP1 | |
| SCHEMBL641321 | 0.73 | TDP1 (0.49) | TSHRALOX15CYP2C19HIF1ATDP1 | |
| SCHEMBL18493237 | 0.73 | ALDH1A1 (0.44) | TSHRCYP2C19TDP1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2020-06-09 | — | — | US | claimed |
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUNDATION (US) | 2019-07-11 | — | — | US | claimed |
| EP-3270870-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2018-01-24 | — | — | EP | claimed |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUND (US) | 2017-02-23 | — | — | US | claimed |
| US-9572753-B2 | Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2017-02-21 | — | — | US | claimed |
| WO-2016160299-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2016-10-06 | — | — | WO | claimed |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION | 2015-09-17 | — | — | US | claimed |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION (US) | 2020-09-24 | — | — | US | disclosed |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUNDATION (US) | 2019-07-11 | — | — | US | disclosed |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2019-03-19 | — | — | US | disclosed |
| EP-3270870-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2018-01-24 | — | — | EP | disclosed |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUND (US) | 2017-02-23 | — | — | US | disclosed |
| US-9572753-B2 | Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2016160299-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | TSHR 4797/4885ALOX15 871/4885CYP2C19 621/4885 |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | TSHR 4797/4885ALOX15 871/4885CYP2C19 621/4885 |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | SUV39H2, CBX3, SUV39H1 | TSHR 4233/4885ALOX15 1307/4885CYP2C19 2145/4885 |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | TSHR 4797/4885ALOX15 871/4885CYP2C19 621/4885 |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | SUV39H2, CBX3, SUV39H1 | TSHR 4233/4885ALOX15 1307/4885CYP2C19 2145/4885 |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ESD, JMJD6, DNPH1 | TSHR 4610/4885ALOX15 614/4885CYP2C19 821/4885 |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | TSHR 4797/4885ALOX15 871/4885CYP2C19 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.