Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843491 | 0.98 | ATM (0.48) | ATMTSHRMAPTNPC1RAB9A | |
| SCHEMBL4710826 | 0.85 | ALDH1A1 (0.50) | ATMTSHRMAPTALDH1A1HTT | |
| SCHEMBL11843484 | 0.78 | TSHR (0.39) | ATMTSHRMAPTNPC1RAB9A | |
| SCHEMBL10824507 | 0.78 | MMP1 (0.42) | ATMTSHRMAPTNPC1RAB9A | |
| SCHEMBL6797392 | 0.78 | TSHR (0.46) | ATMTSHRMAPTNPC1RAB9A | |
| SCHEMBL10982631 | 0.76 | TSHR (0.40) | ATMTSHRMAPTNPC1RAB9A | |
| SCHEMBL13946948 | 0.75 | TSHR (0.41) | ATMTSHRALDH1A1 | |
| SCHEMBL16521732 | 0.74 | MAPT (0.47) | ATMTSHRMAPTNPC1RAB9A | |
| SCHEMBL30434481 | 0.74 | ATM (0.45) | ATMTSHRMAPTNPC1RAB9A | |
| SCHEMBL8992450 | 0.70 | ALDH1A1 (0.47) | ATMTSHRMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549029-A | ORGANOLEPTIC | GIVAUDAN CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |