Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 5/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358191 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TSHRHTTSMN1; SMN2MEN1 | |
| SCHEMBL19617612 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRHTTSMN1; SMN2NPC1 | |
| SCHEMBL2220563 | 0.76 | CYP2C19 (0.42) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1253192 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL28308644 | 0.72 | ALDH1A1 (0.38) | ALDH1A1TSHRATMSMN1; SMN2KMT2A | |
| SCHEMBL16521732 | 0.72 | MAPT (0.47) | ALDH1A1TSHRATMHTTSMN1; SMN2 | |
| SCHEMBL28305527 | 0.71 | CYP2C19 (0.52) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11763498 | 0.71 | CA2 (0.45) | ALDH1A1TSHRATMHTTSMN1; SMN2 | |
| SCHEMBL30434481 | 0.71 | ATM (0.45) | ALDH1A1TSHRATMHTTSMN1; SMN2 | |
| SCHEMBL20556968 | 0.70 | TSHR (0.41) | ALDH1A1TSHRATMHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |