Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449181 | 0.78 | PNP (0.51) | ARKMT2ATDP1 | |
| SCHEMBL11449203 | 0.77 | IDO1 (0.47) | ARKMT2ATDP1 | |
| SCHEMBL11467339 | 0.75 | ALDH1A1 (0.51) | KMT2AALDH1A1CYP2C9HPGD | |
| SCHEMBL10981672 | 0.75 | TDP1 (0.46) | KMT2ATDP1ALDH1A1 | |
| SCHEMBL4418633 | 0.75 | ALDH1A1 (0.53) | KMT2AALDH1A1CYP2C9HPGD | |
| SCHEMBL29408555 | 0.74 | AR (0.50) | ARTDP1ATP4AATP4BALDH1A1 | |
| SCHEMBL3871304 | 0.74 | AR (0.50) | ARTDP1ATP4AATP4BALDH1A1 | |
| SCHEMBL7011364 | 0.72 | PNP (0.54) | KMT2ATDP1ALDH1A1 | |
| SCHEMBL8136867 | 0.71 | KMT2A (0.47) | KMT2ATDP1KDM3BALDH1A1 | |
| SCHEMBL3540299 | 0.70 | KMT2A (0.60) | KMT2ATDP1KDM3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4524071-A | HISTAMINE H2-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1985-06-18 | — | — | US | disclosed |