Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20485154 | 0.91 | CASP3 (0.62) | CTSSCTSLCASP3CTSKCTSB | |
| SCHEMBL10073939 | 0.91 | CASP3 (0.62) | CTSSCTSLCASP3CTSKCTSB | |
| SCHEMBL22811283 | 0.91 | CASP3 (0.62) | CTSSCTSLCASP3CTSKCTSB | |
| SCHEMBL9439818 | 0.90 | MME (0.57) | CTSSCTSLCTSKCTSBCAPN1 | |
| SCHEMBL4558745 | 0.86 | CTSK (0.60) | CTSSCTSLCTSKCTSBCAPN1 | |
| SCHEMBL29577075 | 0.86 | CTSK (0.60) | CTSSCTSLCTSKCTSBCAPN1 | |
| SCHEMBL4561159 | 0.86 | CTSK (0.60) | CTSSCTSLCTSKCTSBCAPN1 | |
| SCHEMBL10608051 | 0.86 | CTSK (0.60) | CTSSCTSLCTSKCTSBCAPN1 | |
| SCHEMBL10452681 | 0.86 | MME (0.56) | CTSSCTSLCTSKCTSBMEN1 | |
| SCHEMBL9440145 | 0.86 | ALDH1A1 (0.59) | CTSSCTSLCTSKCTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517379-A | ARTIFICIAL SWEETENER | PFIZER INC. (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0069811-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-10-24 | — | — | EP | disclosed |
| US-4454328-A | SWEETENERS | PFIZER INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4399163-A | ARTIFICIAL SWEETENERS | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0069811-A1 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1983-01-19 | — | — | EP | disclosed |