Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479484 | 0.84 | LMNA (0.30) | LMNA | |
| SCHEMBL11469934 | 0.79 | HSD17B10 (0.30) | HSD17B10TDP1 | |
| SCHEMBL11479496 | 0.78 | — | — | |
| SCHEMBL7864481 | 0.77 | THRB (0.35) | THRBLMNA | |
| SCHEMBL20224243 | 0.77 | THRB (0.35) | THRBLMNA | |
| SCHEMBL20212051 | 0.77 | — | — | |
| SCHEMBL28376672 | 0.75 | BTN3A1 (0.35) | — | |
| SCHEMBL11469192 | 0.75 | TSHR (0.41) | THRB | |
| SCHEMBL2874716 | 0.74 | ALDH1A1 (0.43) | THRBLMNAHSD17B10TDP1 | |
| SCHEMBL1878811 | 0.74 | ALDH1A1 (0.43) | THRBLMNAHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503239-A | Process for the preparation of ethylenic halogenoacetals | RHONE-POULENC SANTE (FR) | 1985-03-05 | — | — | US | disclosed |
| US-4209644-A | PERFUMES | TEIJIN LIMITED (JP) | 1980-06-24 | — | — | US | disclosed |