⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977643 | 0.90 | NPC1 (0.38) | — | |
| SCHEMBL10978708 | 0.89 | ALDH1A1 (0.47) | — | |
| SCHEMBL10983108 | 0.88 | ALDH1A1 (0.44) | — | |
| SCHEMBL10981373 | 0.88 | MAPT (0.36) | — | |
| SCHEMBL11054368 | 0.82 | KMT2A (0.42) | — | |
| SCHEMBL10990927 | 0.80 | ALDH1A1 (0.46) | — | |
| SCHEMBL10979543 | 0.79 | ALDH1A1 (0.61) | — | |
| SCHEMBL10983314 | 0.78 | ALDH1A1 (0.47) | — | |
| SCHEMBL10984221 | 0.78 | NPC1 (0.39) | — | |
| SCHEMBL11194217 | 0.78 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499279-A | ANTIDIABETIC AND HYPOGLYCEMIC AGENTS | SANDOZ, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4419353-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1983-12-06 | — | — | US | disclosed |
| US-4397850-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4336379-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1982-06-22 | — | — | US | disclosed |