Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986261 | 0.90 | — | — | |
| SCHEMBL10984221 | 0.88 | NPC1 (0.39) | NPC1RAB9A | |
| SCHEMBL10989873 | 0.88 | BRD4 (0.43) | — | |
| SCHEMBL11079151 | 0.87 | NPC1 (0.40) | NPC1RAB9A | |
| SCHEMBL10978708 | 0.87 | ALDH1A1 (0.47) | — | |
| SCHEMBL10983108 | 0.87 | ALDH1A1 (0.44) | NPC1RAB9A | |
| SCHEMBL11086175 | 0.85 | GABRA1 (0.39) | NPC1RAB9A | |
| SCHEMBL10984689 | 0.84 | MAPK14 (0.39) | — | |
| SCHEMBL10977892 | 0.83 | POLB (0.43) | NPC1RAB9A | |
| SCHEMBL11053638 | 0.83 | GAA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499279-A | ANTIDIABETIC AND HYPOGLYCEMIC AGENTS | SANDOZ, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4419353-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1983-12-06 | — | — | US | disclosed |
| US-4397850-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4336379-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1982-06-22 | — | — | US | disclosed |