Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832100 | 0.91 | ALDH1A1 (0.50) | KMT2AMEN1HTTALDH1A1PTGS1 | |
| SCHEMBL11053638 | 0.90 | GAA (0.43) | — | |
| SCHEMBL11054882 | 0.89 | TUBB4A (0.46) | KMT2AMEN1HTTALDH1A1HPGD | |
| SCHEMBL11049245 | 0.88 | PADI4 (0.45) | KMT2AMEN1HTTALDH1A1HPGD | |
| SCHEMBL10986261 | 0.82 | — | — | |
| SCHEMBL11054385 | 0.78 | CSF1R (0.46) | KMT2AMEN1HTTPADI4BRD4 | |
| SCHEMBL11054892 | 0.78 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1PTGS1 | |
| SCHEMBL10986271 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HSD17B10CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11046939 | 0.77 | TUBB4A (0.48) | KMT2AMEN1HTTALDH1A1HPGD | |
| SCHEMBL10832434 | 0.77 | GAA (0.47) | KMT2AMEN1HTTBRD4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453001-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4415568-A | ANTIDIABETIC AND HYPOGLYCEMIC AGENTS | SANDOZ, INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4336378-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1982-06-22 | — | — | US | disclosed |