Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | HRH1 | P35367 | 3/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10990237 | 0.97 | PRKACA (0.52) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL10992605 | 0.94 | PRKACA (0.54) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL16826405 | 0.74 | DRD2 (0.59) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL7033807 | 0.74 | HTR1A (0.80) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL11199379 | 0.71 | HTR1A (0.59) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL10844253 | 0.71 | HRH3 (0.49) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL10986152 | 0.71 | PRKACA (0.48) | HTR1ADRD2HTR2ADRD3PRKACA | |
| SCHEMBL16825679 | 0.71 | HTR1A (0.54) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9349929 | 0.70 | SIGMAR1 (0.69) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9349920 | 0.70 | SIGMAR1 (0.69) | HTR1ADRD2HTR2ADRD3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562189-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-12-31 | — | — | US | claimed |