Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.44 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.44 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992698 | 0.88 | PARP1 (0.49) | KMOALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL10985563 | 0.83 | KDM4E (0.48) | ALDH1A1LMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10995233 | 0.82 | ADORA2A (0.52) | KMOADORA2APIN1DHODHPTGER1 | |
| SCHEMBL10986803 | 0.80 | KMO (0.49) | KMOLMNANPSR1KMT2AADORA2A | |
| SCHEMBL8474142 | 0.80 | PDE4A (0.41) | ALDH1A1LMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10992005 | 0.78 | ADORA2A (0.48) | ALDH1A1LMNANPSR1KMT2AADORA2A | |
| SCHEMBL18584515 | 0.75 | DHODH (0.44) | NPSR1KDM4EDHODHPTGER1MAPT | |
| SCHEMBL10983261 | 0.75 | ADORA2A (0.45) | ALDH1A1LMNANPSR1KMT2AADORA2A | |
| SCHEMBL2372855 | 0.73 | DHODH (0.71) | KMT2ADHODH | |
| SCHEMBL10995427 | 0.73 | DHODH (0.49) | KMOLMNANPSR1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499094-A | PREVENTION OF RESPIRATORY, UROGENITAL, CARDIOVASCULAR AND IMMUNOLOGICAL DISORDERS WHEN USING FOR BENZDIAPINES | PHARMUKA LABORATOIRES (FR) | 1985-02-12 | — | — | US | disclosed |